Profile of Sonia Tamanna (on study leave)

... Name Sonia Tamanna (on study leave)
Designation Assistant Professor
Last Degree M.S. (DU)
   

 

Name: SONIA TAMANNA

Designation:  Assistant Professor

Contact Address:

Department of Biochemistry and Molecular Biology 

University of Dhaka, Dhaka-1000, Bangladesh.

E-mail: sonia@du.ac.bd

 

CURRENT RESEARCH ACTIVITIES:

Regulation and role of the angiotensin converting enzyme 2 (ACE2)/Angiotensin (Ang)-(1-7) pathway in the pathogenesis of preeclampsia

Preeclampsia, a hypertensive disorder of pregnancy, is clinically defined as maternal hypertension, proteinuria, and generalized edema occurring after the 20th week of gestation. Preeclampsia is a leading cause of maternal mortality and contributes significantly to neonatal morbidity and mortality. Thus, the prevention of preeclampsia could have a significant impact on maternal and neonatal outcome. Nevertheless, the pathophysiology of preeclampsia remains poorly understood.

Although preeclampsia is often considered a multisystem disorder, one of the known causes of this disease is impaired placentation and impaired maternal uterine spiral artery remodeling. An imbalance in the circulating and intrauterine renin-angiotensin systems (RAS) has also been demonstrated.This project aims to specifically focus on the ACE2/Ang-(1-7) pathway, which counteracts the vasoconstrictive and hypertensive effects of Ang II/AT1R to determine how it is regulated, and whether it contributes to the normal pregnancy.

QUALIFICATIONS:

  • Masters of Science (M .Sc) in Biochemistry and Molecular Biology,University of Dhaka, Bangladesh.
  • Bachelor of Science (B. Sc) Honors (4 Years Integrated Course) in Biochemistry and Molecular Biology,University of Dhaka, Bangladesh.

FIELD OF RESEARCH:

Project-1:Preeclampsia associated complications: during a d after pregnancy”.This project was to evaluate the association of gestational diabetes, thyroid dysfunction and DNA damage in the pathogenesis of preeclampsia. The results of these investigations suggested that    hypothyroidism, gestational diabetes and DNA damage may play a significant role in the pathogenesis of preeclampsia.

Project -2: ”Oxidative stress and anti-oxidant status of cervical patient at different stages of disease in Bangladesh”. This project was to evaluate the association of gestational diabetes, thyroid dysfunction and DNA damage in the pathogenesis of preeclampsia. The results of these investigations suggested that    hypothyroidism, gestational diabetes and DNA damage may play a significant role in the pathogenesis of preeclampsia.

Project-3:Screening of Nutritionally Rich and Low Glycemic Index Bangladeshi Rice Varieties funded by Food and Agriculture Organization (FAO). The aim of this project was to investigate a complete nutritional status of selected rice varieties like {protein and starch content and their in vitro digestibility, vitamins (B1, B2 and niacin) and minerals (Ca, Zn, Fe, Se).} and determined the glycemic response of these varieties. 

Project-4: Oxidative stress and anti-oxidant status in neonates born to preeclamptic other . This project was to investigate the effect of preeclampsia on neonates and for this purpose explored oxidative stress and anti-oxidant status in the fetal circulation in pre-eclampsia. The results of these investigations suggest that oxidative stress and antioxidant status are altered towards proatherogenic level in cord blood of pre-eclamptic women which may ultimately be responsible for different complications of newborn babies of pre-eclamptic mothers.

Project-5:“Superoxide Dismutase (SOD) Activity and Changes of Some Micronutrients in Preeclampsia”. Serum  total protein, albumin, serum iron concentration, percent saturation of transferring, total iron binding capacity, unsaturated iron-binding capacity, Cu, Ca, Mg, Zn, Cd and superoxide dismutase (SOD) activity were measured.The results of these investigation suggested that changes of micronutrients may play a significant role in the pathogenesis of preeclampsia. The findings have been published in Journal.

PROFESSIONAL EXPERIENCE:

(I)Teaching Expertise:

  • Assistant Professor, Department of Biochemistry & Molecular Biology, University of Dhaka, 30thApril, 2013 – present.
  • Lecturer, Department of Biochemistry & Molecular Biology, University of Dhaka, 1st July 2010 – 29th April 2013.
  • Adjunct Faculty, Department of Marketing, University of Dhaka, 1st July2014- June 2015. 
  • Lecturer, Department of Biochemistry, Gonoshasthaya Samaj Vittik Medical College, Gono Bishwabidyalaya (University), 13th November 2008 – 30th June 2010.     

(II)Administrative Expertise:

Served as a part time House tutor at Ruqayyah Hall, University Of Dhaka from 4th October 2011 to August 31st, 2015.

 

RESEARCH PUBLICATIONS:

  1. Md. Zakir H. Howlader, Sayma Parveen, Sonia Tamanna, Tanzir A. Khanand   Firoza Begum (2009). “Oxidative Stress and Antioxidant Status in Neonates Born to Pre-eclamptic Mother”, Journal of Tropical Pediatrics, Vol. 55, No. 6.
  2. M Zakir H Howlader , Sonia Tamanna , Sayma Parveen ,  Hossain U Shekhar , M Alauddin , Firoza Begum(2009).  “Superoxide Dismutase (SOD) Activity and Changes of Some Micronutrients in Preeclampsia”, Bangladesh Journal of Medical Science,Volume-15, No.2
  3. Md. Masud Rana , Aysha Ferdoushi , Sonia Tamanna , Farah Sabrin , Nushrat Nahida Afroz (2012)“Assessment of Nutritional Status of 5-10yearsGaro Children in Sherpur District, Bangladesh”, International Journal of Biosciences(IJB)2(11):66-73.
  4. Sonia Tamanna, Sayma Parvin, Sanjay Kumar, Alak K Dutta,Aysha Ferdoushi, M Ali Siddiquee, Sunil K Biswas and M  Zakir H Howlader (2013)“Content of Some Minerals and Their  Bioavailability In Selected Popular Rice Varieties From Bangladesh”, International Journal of Current Microbiology and Applied Sciences, 2(7):35-43.
  1. Tamanna S , Rana MM , Ferdoushi A , Ishtiyaq Ahmad SA , Rahman M , Rahman A(2013).  Assessment of Nutritional Status among Adolescent Garo in Sherpur District, Bangladesh, Bangladesh Journal of Medical Science, Vol.12, No. 3: pp. 269-275
  1. Pratul Dipta Somadder,Md. Masud Rana, Aysha Ferdoushi, Sonia Tamanna, Shah Adil Ishtiyaq Ahmad , Murshida Khanam (2013)“Comparative Assessment of Nutritional       Status       among      Children      ofbThree      Tribal       Populations        of Rangamati District, Bangladesh”, International Journal of Biosciences (IJB) 3 (1): 142149.

CONFERENCES /WORKSHOPS/ TRAINING:

  1. Active participation in Marc Nanjing University-RIKEN BRC Mouse Resource Workshop 2016 on July 25-27, 2016 at RIKEN Bioresource Center, Japan.
  2. Active participation and served as an organizing member of National Conference on “Biochemistry Industry and Sustainable Economy” Organized by Bangladesh Society for Biochemistry and Molecular Biology (BSBMB) in collaboration with Department of Biochemistry and Molecular Biology. Date: March 21, 2015, Venue: Nabab Nawab Ali Chowdhury Senate Bhaban of Dhaka University.
  3. Active participation in International symposium on “Cancer and developmental Biology: Latest clinical and biochemical approaches” organized by the Bangladesh Society for Biochemistry and Molecular Biology. Date: 29-31 January, 2010 Venue: Nabab Nawab Ali Chowdhury Senate Bhaban of Dhaka University.
  4. Active participation and contribution to the success of the Workshop on Designing Biochemistry Courses Organized by: Bangladesh Society for Biochemistry and Molecular Biology (BSBMB) on 18th and 19th December 2011with funding from the IUBMB and FAOBMB( Federation of Asian and Oceanic Biochemists and Molecular Biologists).
  5. Successful completion of fifteen hours training program on “SPSS and Applied Statistics” conducted by Institute of Statistical Research and Training(ISRT), University of Dhaka from 19th June to 24th June, 2012.

AFFILIATIONS:

  1.   Member of American Society for Microbiology (ASM) Membership ID: 57437832
  2. Member of Bangladesh Society for Biochemistry and Molecular Biology(BSBMB) 
  3. Member of American Psychological association(APA)